N-Nitroso Diisopropylamine (NDIPA)

Name: N-Nitroso Diisopropylamine (NDIPA)
Brand: Ozone Specialities
Price: 1700 INR
Availability: InStock

Price 1700 INR/ Kilograms

Get a Price/Quote

MOQ : 25 Kilograms

N-Nitroso Diisopropylamine (NDIPA) Specification

Molecular Weight
130.19 g/mol Grams (g)

Shelf Life
24-36 Months

Ph Level
6.0 7.0

Taste
Other

Structural Formula
[(CH)CH]N-N=O

HS Code
292990

Melting Point
46C to 49C

Boiling point
194.5C at 760 mmHg

EINECS No
210-001-4

Solubility
Highly soluble in Methanol, Acetonitrile, and Chloroform

Loss on Drying
0.5%

Smell
Other

Particle Size
Standard Fine Powder/Crystals

Heavy Metal (%)
0.001%

Storage
Freezer

Molecular Formula
CHNO

Medicine Name
N-Nitroso Diisopropylamine (NDIPA) Reference Standard

Chemical Name
N-Nitrosodiisopropylamine

CAS No
601-77-4

Type
Pharmaceutical Intermediates

Grade
Other

Usage
Laboratory research, drug impurity profiling, HPLC-MS/MS testing calibration

Purity(%)
98.0%

Appearance
Crystalline solid

Physical Form
Solid

N-Nitroso Diisopropylamine (NDIPA) Trade Information

Minimum Order Quantity
25 Kilograms

Payment Terms
Cash in Advance (CID)

Supply Ability
500 Kilograms Per Month

Delivery Time
1 Week

Sample Available
Yes

Sample Policy
Contact us for information regarding our sample policy

Packaging Details
Amber glass vials (1 mL, 10 mg, or 50 mg), packed under inert gas (nitrogen/argon), sealed in thermocol boxes with ice packs.

Main Domestic Market
All India

Certifications
coa,msds

N-Nitroso Diisopropylamine (NDIPA) About

N-Nitroso Diisopropylamine (NDIPA) is a chemical compound belonging to the nitrosamine class, recognized globally as a potential mutagenic impurity and suspected carcinogen in pharmaceutical products. It gained significant regulatory attention following the discovery of nitrosamine impurities in widely prescribed medications like sartan-based blood pressure drugs.

Pharmaceutical Reference Standards: It serves as a Certified Reference Material (CRM) to test and quantify impurities in drug batches. Chemists use it to ensure compliance with threshold limits set by international regulators.
Analytical Testing Methods: Labs utilize NDIPA standards to develop and validate high-sensitivity testing methods. These typically include High-Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS) and Gas Chromatography.
Toxicology and Mutagenicity Studies: Researchers study NDIPA to map the metabolic pathways and structural risk factors of nitrosamines. For instance, toxicological assessments show it has lower mutagenicity compared to nitrosamines with more -hydrogen atoms, helping refine structural risk modeling.